BREAKING NEWS: JURNAL REKONSTRUKSI DAN ESTETIK (JRE) IS NOW OFFICIALLY INDEXED IN SINTA!

 

Proud Achievement: Jurnal Rekonstruksi dan Estetik Achieves SINTA 3 Accreditation

We are proud to announce that Jurnal Rekonstruksi dan Estetik (JRE) has been officially accredited at SINTA 3, a national recognition granted by the Ministry of Higher Education, Science, and Technology of the Republic of Indonesia.

This accreditation is based on the Decree of the Directorate General for Research and Development No. 286/DST/C3/HM.01.00/2026, issued on 7 April 2026. The accreditation applies retroactively from Volume 8 Number 1 (2023) and will remain valid until Volume 12 Number 2 (2027).

This milestone represents a significant step forward in our continuous efforts to maintain and enhance the quality of scholarly publishing, particularly in the fields of plastic reconstructive and aesthetic surgery. It reflects our strong commitment to upholding rigorous peer-review standards, ethical publication practices, and the dissemination of impactful scientific knowledge.

We would like to express our sincere appreciation to our editorial board members, reviewers, authors, and the broader academic community for their invaluable contributions, trust, and collaboration. Your support has been instrumental in achieving this recognition.

Moving forward, JRE remains dedicated to fostering high-quality research and supporting both academic advancement and clinical practice. We warmly invite researchers, clinicians, and scholars to contribute their work and be part of our growing scientific community.

For more information and submission guidelines, please visit our official website:

https://e-journal.unair.ac.id/JRE/index

For inquiries, feel free to contact us via:

Email: jre@journal.unair.ac.id

You can also stay connected through our social media platforms:

Instagram: @jre.unair

X (Twitter): @jre_unair

Facebook: Jre Unair

LinkedIn: @jreunair

Blog: jreunair

Thank you for your continued support.

#UniversitasAirlangga #UnairHEBAT #JREUNAIR #ExcellentWithMorality #QSWorldUniversityRankings #UNAIR #AcademicExcellence #WorldClassUniversity #SmartUniversity #Research #Publication #ScholarUnair #JurnalUNAIR

CALL FOR PAPERS VOL 11 NO 1 JUNE 2026

Call for Papers: Jurnal Rekonstruksi dan Estetik Vol. 11 No. 1 June 2026
We are now open for manuscript submissions for our upcoming June issue!

Accepting:
Original articles, systematic review, case series, review articles, literature reviews, and meta-analyses.

Focus Areas:
Burn & wound care, hand surgery, microsurgery, oncoplastic surgery, craniofacial reconstruction, external genitalia reconstruction, and aesthetic procedures.

Submit your best work and contribute to the growing body of knowledge in reconstructive and aesthetic surgery!

Online Submission: https://e-journal.unair.ac.id/JRE/Online_Submission
Author Guidelines: https://e-journal.unair.ac.id/JRE/Guideline_for_Authors
Questions? Email us at: jre@journal.unair.ac.id

Discover more at: https://e-journal.unair.ac.id/JRE/index

#CallForPapers #JurnalRekonstruksiDanEstetik #JREUnair #PlasticSurgery #AestheticSurgery #Microsurgery #BurnCare #MedicalResearch #Indonesia #OpenAccessJournal #SubmitNow

 

COMPARATIVE OUTCOMES OF EARLY VERSUS DELAYED WOUND GRAFTING IN BURN PATIENTS: A SYSTEMATIC REVIEW AND META-ANALYSIS

 

🔥 Does Timing Matter in Burn Wound Grafting? Evidence from a Meta-Analysis

Burn injuries remain a major global health burden, with more than 265 million cases annually worldwide. Surgical skin grafting is a cornerstone in burn management, yet the optimal timing of grafting, whether early or delayed continues to be debated, especially in settings with limited resources.

This systematic review and meta-analysis published in Jurnal Rekonstruksi dan Estetik (JRE) evaluates the clinical and functional outcomes of early versus delayed wound grafting in burn patients.

📄 Article Title:
Comparative Outcomes of Early Versus Delayed Wound Grafting in Burn Patients: A Systematic Review and Meta-Analysis
🔗 DOI: https://doi.org/10.20473/jre.v10i2.75022

📌 Why This Study Matters

Early excision and grafting,traditionally performed within 48 hours to 7 days is believed to:

• Reduce infection risk

• Shorten hospital stay

• Improve functional recovery

• Lower morbidity and mortality

However, factors such as hemodynamic instability, inadequate resuscitation, and limited surgical resources often delay intervention, particularly in low- and middle-income countries. This study provides evidence-based guidance to support clinical decision-making.

🔍 Methods at a Glance

• Study design: Systematic review and meta-analysis

• Search period: July 2024 – January 2025

• Study types included:

  • Randomized controlled trials

  • Cohort studies

  • Observational studies

• Comparison groups:

  • Early grafting (within 3–7 days)

  • Delayed grafting (after 7 days)

• Outcomes assessed:

  • Length of hospital stay

  • Infection rates

  • Blood loss

  • Limb and hand function (TAM & grip strength)

📊 Key Results

• 250 studies identified, 7 studies met inclusion criteria

• Hospital stay:

  • Early grafting significantly reduced hospitalization by
    8.89 days
    (95% CI: −12.88 to −4.89)

• Functional outcomes:

  • Early grafting showed significantly better Total Active Movement (TAM)
    MD: 22.10 (95% CI: 17.95 to 26.24)

• Other outcomes:

  • No statistically significant differences between early and delayed grafting in:

    • Blood loss

    • Infection rates

    • Post-operative grip strength

🧠 Clinical Interpretation

✅ Early wound grafting offers clear benefits in:

• Faster recovery

• Shorter hospital stay

• Improved postoperative limb mobility

⚠️ However, early grafting did not significantly outperform delayed grafting in terms of infection rates or blood loss, highlighting the importance of patient condition and surgical readiness rather than timing alone.

🎯 Key Takeaways

• Early grafting improves functional recovery and hospitalization outcomes

• Timing should be balanced with patient stability and resource availability

• Supports early intervention when clinically feasible

• Calls for further high-quality studies to refine timing protocols

📚 Published in: Jurnal Rekonstruksi dan Estetik
✍️ Authors: Rafeni Bunga, Beta Subakti Nata’admaja
🏥 Affiliations:

• Mayapada Hospital Surabaya

• Dr. Soetomo General Academic Hospital, Surabaya

🔗 Read the full article:
https://doi.org/10.20473/jre.v10i2.75022

#BurnInjury #SkinGrafting #EarlyGrafting #DelayedGrafting #BurnManagement #ReconstructiveSurgery #PlasticSurgery #SystematicReview #MetaAnalysis #EvidenceBasedMedicine #FunctionalOutcome
 #WoundCare #HospitalStay #ClinicalDecisionMaking #JRE #JREUnair

THERAPEUTIC POTENTIAL OF SNAIL MUCUS IN WOUND HEALING : A SYSTEMATIC REVIEW AND META-ANALYSIS

 

✨ Exploring Snail Mucus as a Novel Bioactive Agent in Wound Repair

Wound healing is a complex biological process that requires a coordinated interaction between inflammation control, collagen synthesis, angiogenesis, and tissue remodeling. Despite advances in wound care, delayed healing remains a significant clinical challenge prompting ongoing exploration of natural bioactive substances that can support tissue regeneration.

A recent article published in Jurnal Rekonstruksi dan Estetik systematically evaluates the therapeutic potential of snail mucus extract as a wound-healing agent through a systematic review and meta-analysis of randomized controlled trials (RCTs).

📄 Article Title:
Therapeutic Potential of Snail Mucus in Wound Healing: A Systematic Review and Meta-Analysis
🔗 DOI: https://doi.org/10.20473/jre.v10i2.72008

📌 Why This Study Is Important

Proteins play a pivotal role in wound repair, mediating cellular migration, extracellular matrix formation, and tissue remodeling. Snail mucins, large glycosylated proteins found in snail mucus, have been reported to:

• Stabilize protein structures

• Enhance cell–cell recognition

• Modulate viscosity and solubility

• Promote collagen production

• Reduce inflammatory responses

This study provides a rigorous evidence-based evaluation of these proposed benefits.

🔍 Key Findings from the Meta-Analysis

🔹 Study Design and Methodology

• Meta-analysis of randomized controlled trials

• Databases searched:

  • PubMed

  • ProQuest

  • Web of Science

  • ScienceDirect

  • Scopus

  • EBSCOHost

  • ClinicalTrials.gov

• Methodological framework:

  • PRISMA guidelines

  • PICO framework

  • Quality assessment using the JADAD scale

🔹 Quantitative Results

• 3 RCTs (2021–2023)

• Total of 60 animal subjects (rats)

• Snail mucus group showed a significantly faster wound healing rate compared to controls:

  • Mean Difference (MD): −3.21%

  • 95% CI: −3.72 to −2.69%

  • P < 0.00001

These results indicate a robust and statistically significant effect.

🧬 Biological Mechanisms Behind Snail Mucus

The bioactive components of snail mucus contribute to wound healing by:

• Enhancing collagen synthesis

• Reducing local inflammation

• Supporting cellular proliferation and migration

• Improving tissue remodeling dynamics

These mechanisms align well with modern principles of regenerative medicine and biomaterial-based wound therapy.

⚠️ Translational Considerations

While the findings strongly support the wound-healing efficacy of snail mucus in animal models, the authors emphasize the need for:

• Well-designed clinical trials

• Standardized formulations

• Safety and dosage evaluations in humans

🎯 Why This Article Is Worth Reading and Citing

• Provides pooled quantitative evidence via meta-analysis

• Highlights snail mucus as a promising natural wound-healing agent

• Integrates molecular rationale with experimental outcomes

• Relevant to plastic surgeons, wound care specialists, and regenerative medicine researchers

• Opens avenues for future translational and clinical research

📚 Published in: Jurnal Rekonstruksi dan Estetik
✍️ Authors: Febe Alodia Widjaja et al.
🏥 Affiliations: Universitas Airlangga, Universitas Airlangga Hospital, Dr. Soetomo General Academic Hospital, University of Twente

🔗 Read the full article:
https://doi.org/10.20473/jre.v10i2.72008

#WoundHealing #SnailMucus #RegenerativeMedicine #NaturalBioactives #CollagenSynthesis
#InflammationControl #MetaAnalysis #SystematicReview #EvidenceBasedMedicine #PlasticSurgery
#ReconstructiveSurgery #WoundCare #BiomedicalResearch #TranslationalResearch #MedicalPublication #JRE #JREUnair

EFFECTIVENESS OF ANTIBIOTIC PROPHYLAXIS IN MAXILLOFACIAL TRAUMA SURGERY: A SYSTEMATIC REVIEW

 

✨ Reassessing Routine Antibiotic Use in Maxillofacial Trauma Surgery

Maxillofacial trauma surgery frequently involves contaminated wounds, complex anatomy, and prolonged operative time, factors traditionally associated with a higher risk of surgical site infections (SSIs). For this reason, antibiotic prophylaxis has long been prescribed as routine practice. However, growing concerns regarding antimicrobial resistance, unnecessary costs, and unclear clinical benefit have prompted critical re-evaluation of this approach.

A recent systematic review published in Jurnal Rekonstruksi dan Estetik addresses this ongoing debate by examining whether prophylactic antibiotics truly reduce SSI rates in maxillofacial trauma surgery.

📄 Article Title:
Effectiveness of Antibiotic Prophylaxis in Maxillofacial Trauma Surgery: A Systematic Review
🔗 DOI: https://doi.org/10.20473/jre.v10i2.72261

📌 Why This Study Matters

Despite widespread use, recommendations on whether, when, and how long antibiotics should be given in maxillofacial trauma surgery remain inconsistent. Overprescription not only increases healthcare costs but also contributes to the global threat of antimicrobial resistance.

This systematic review provides an evidence-based assessment to support more rational, patient-centered antibiotic use.

🔍 Key Findings from the Review

🔹 Study Design and Methodology

• Systematic search conducted using Google Scholar

• Selection based on PICO framework

• Included observational cohort studies

• Study quality assessed using the JBI Critical Appraisal Checklist for Cohort Studies

A total of six studies met the inclusion criteria.

🔹 Do Prophylactic Antibiotics Reduce SSIs?

• Five of six studies found no significant reduction in SSI rates with prophylactic antibiotics

• Lack of benefit observed regardless of:

  • Timing (preoperative vs postoperative)

  • Duration of antibiotic administration

• Only one study reported a statistically significant reduction in SSIs with preoperative prophylaxis

Variations in surgical technique, antibiotic regimens, patient characteristics, and study design likely contributed to inconsistent findings.

🔹 Postoperative Antibiotics: More Harm Than Benefit?

The review highlights that postoperative antibiotic regimens:

• Do not reduce SSI rates

• Increase treatment costs

• Contribute to antimicrobial resistance

These findings challenge the routine use of prolonged antibiotics after maxillofacial trauma surgery.

⚠️ Clinical Implications

Rather than universal prophylaxis, the evidence supports a selective, risk-based approach, reserving antibiotics for:

• Immunocompromised patients

• Grossly contaminated wounds

• Extensive soft-tissue injury

• Prolonged or complex surgical procedures

Such an approach aligns with modern principles of antibiotic stewardship and evidence-based surgical care.

🎯 Why This Article Is Worth Reading and Citing

• Clarifies controversies surrounding antibiotic prophylaxis in maxillofacial trauma

• Supports judicious and selective antibiotic use

• Reinforces antimicrobial stewardship principles

• Relevant for oral and maxillofacial surgeons, plastic surgeons, and trauma teams

• Highlights the need for high-quality randomized controlled trials

📚 Published in: Jurnal Rekonstruksi dan Estetik
✍️ Authors: Naufal Agus Isamahendra, Muhammad Tidar Abiyyu, Iswinarno Doso Saputro, Yanuar Ari Pratama
🏥 Institution: Faculty of Medicine, Universitas Airlangga & Dr. Soetomo General Academic Hospital

🔗 Read the full article:
https://doi.org/10.20473/jre.v10i2.72261

#MaxillofacialTrauma #AntibioticProphylaxis #SurgicalSiteInfection #AntimicrobialStewardship
#EvidenceBasedSurgery #MaxillofacialSurgery #PlasticSurgery #ReconstructiveSurgery #TraumaSurgery #InfectionControl #ClinicalResearch #SystematicReview #MedicalPublication
#GlobalHealth #PatientSafety #RationalAntibioticUse #AMR #HealthcareQuality #JRE #JREUnair