THE EFFECT OF PROPANOLOL ON C-REACTIVE PROTEIN IN PATIENTS WITH SEVERE BURNS AT DR. SOETOMO GENERAL ACADEMIC HOSPITAL, SURABAYA, INDONESIA
🔥Discover groundbreaking research on propranolol's role in managing hypermetabolism in severe burn patients at Dr. Soetomo General Academic Hospital! 🔬
Burn injuries in Indonesia are on the rise due to population growth and industrialization, presenting significant health challenges with a notable mortality rate. Severe burns trigger hypermetabolic states that adversely affect various physiological functions, necessitating effective management strategies. This study investigates the impact of propranolol on hypermetabolism in severe burn patients through clinical and laboratory assessments.
Propranolol administration over 15 days significantly reduced C-reactive protein (CRP) levels, indicating improved metabolic control. An experimental study at Dr. Soetomo General Academic Hospital utilized a pre- and post-test control group design with burn patients covering 25 to 60 percent total body surface area (TBSA). Measurements at baseline, day 7, and day 14 evaluated treatment outcomes.
Sixteen participants were divided into treatment and control groups. Significant reductions in CRP levels were observed in the treatment group on days 7 and 14 (p < 0.05), demonstrating propranolol's effectiveness in mitigating hypermetabolic responses. Other parameters like Mid Arm Circumference and albumin levels showed varied responses, underscoring CRP as a robust indicator of treatment efficacy.
This study marks a significant advancement in burn injury management, showcasing propranolol's potential in alleviating hypermetabolic states. It provides compelling evidence that propranolol administration effectively attenuates hypermetabolic responses in severe burn patients. Such findings highlight propranolol as a promising therapeutic adjunct in managing severe burn injuries.
Explore our latest research uncovering the efficacy of propranolol in mitigating hypermetabolic responses in severe burn patients and reshaping burn care at Dr. Soetomo General Academic Hospital. Join us in exploring cutting-edge research and advancements in burn care, and stay tuned for updates on improving patient outcomes through innovative treatments.
Read More: https://e-journal.unair.ac.id/JRE/article/view/24352
More article: https://e-journal.unair.ac.id/JRE/
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